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Dozens of FDA-approved estrogen, progesterone, and combination products exist in various strengths and delivery systems

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For many people, those who havent responded to lifestyle interventions, those with weight-related co-morbidities, those facing metabolic complications, they represent a genuinely transformative option

The SUSTAIN and PIONEER trial series highlighted not only its effectiveness in these areas but also its cardiovascular safety profile, making it a suitable option for a broad spectrum of patients, including those with a high risk of cardiovascular events

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